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" The Science Behind the Beauty "
 
The Science behind TNS Recovery Complex® with Nouricel® - MD

NouriCel-MD is a human growth factor solution containing amino acids, vitamins, antioxidants and several cytokines/growth factors. NouriCel-MD is obtained from the growth medium of cultured neonatal foreskin fibroblasts. Originally developed by Advanced Tissue Sciences (La Jolla, CA), a three-dimentional artificial matrix is used to grow neonatal foreskin fibroblasts into what ultimately becomes an artificial dermis. As the fibroblast grow and proliferate on the matrix, they generate extracellular substances such as naturally produced collagen, growth factors and cytokines. This is NouriCel-MD, a unique product which capitalizes on the physiological advantage of many tissue factors in one solution that interact to minimally stimulate epidermal and dermal tissue. NouriCel-MD is a proprietary mixture of over 110 stable growth factors and cytokines believed to play a crucial role in the skin tissue growth and repair

Some of the components of NouriCel-MD are:
Growth Factor / Cytokine:
  • bFGF (FGF-2), FGF-4, FGF-6, KGF (FGF-7), FGF-9 (Fibroblast Growth Factor)
  • HGF (Hepatocyte Growth Factor)
  • PDGF AA, PDGF BB, PDGF Rb (Platelet Derived Growth Factor)
  • IGF1, IGFBP1, IGFBP2, IGFBP3, IGFBP6 (Insulin Like Growth Factor)
  • TGFß1, TGTß2, TGFß3 (Transforming Growth Factor)
  • TIMP1, TIMP2 (Tissue Inhibitor of Metalloproteinases)
  • VEGF (Vascular Endothelial Growth Factor)
  • PLGF (Placenta Growth Factor)
  • BMP7 (Bone Morphogenetic Protein)
  • IL1a, IL1ß, IL2, IL3, IL4, IL5, IL6, IL8, IL11, IL12, IL15, IL16 (Interleukins)
  • IL10, IL13 (Interleukins)
  • Leptin
  • GCSF, GM-CSF, M-CSF (Colony Stimulating Factor)

Function related to skin tissue regeneration:
  • promote skin cell growth and tissue repair
  • promote three dimentional tissue growth
  • regulate cell growth and division in wound healing
  • promote cell growth and multiplication
  • stimulate collagen deposition and cell growth
  • prevent breakdown of collagen and hyaluronic acid
  • increase blood vessels permeability to improve tissue nutrition
  • promote endothelial cell growth
  • promote development of nerve cells in developing tissue
  • induce cells to produce growth factors and cytokines
  • produce anti-inflammatory effect
  • induce wound re-epithelialization and skin repair
  • stimulate the development of neutrophils and macrophages